anti-interleukin-6 for COVID-19 - living meta-analysis of clinical studies

meta|evidence COVID-19

Living systematic review and meta-analysis

vs. potential COVID-19 treatments
vs. anti-inflammatoty and immuno-therapy
vs. corticosteroids
vs. dexamethasone
vs. Immunosuppressants drugs
vs. anti-interleukin-6
vs. tocilizumab
vs. antiviral and associated therapy
vs. favipiravir
vs. control
vs. placebo
vs. standard of care

All
COVID 19 hospitalized
COVID 19 all comers
COVID-19 mild to moderate
COVID-19 severe or critically
COVID 19 outpatients
COVID-19 (hospitalized or not)
COVID-19 prophylaxis (children)
COVID-19 prophylaxis (excluding children)
infections other than COVID-19
Long COVID-19
preventing respiratory virus transmission
root
secondary prevention

Studies
Mapping
Meta-analysis
Excluded 0

table network network 2

display ongoing demontrated benefit only

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TOCIVID (sarilumab), 0 NCT04322773

sarilumab vs. standard of care

COVID 19 all comers

sarilumab phase 2 high dose, 0 NCT04315298

sarilumab high dose (400mg) vs. placebo

COVID 19 all comers

sarimulab phase 2 low dose, 0 NCT04315298

sarilumab low dose (200mg) vs. placebo

COVID 19 all comers

ChiCTR2000030894 -TOCI, 0 ChiCTR2000030894

tocilizumab vs. favipiravir

COVID 19 all comers

NCT04356937, 0 NCT04356937

tocilizumab vs. placebo

COVID 19 all comers

BACC Bay Tocilizumab Trial, 2020 NCT04356937

tocilizumab vs. placebo

COVID 19 all comers

TOCIVID (tocilizumab), 0 NCT04322773

tocilizumab vs. standard of care

COVID 19 all comers

TOCOVID, 0 NCT04332094

tocilizumab vs. standard of care

COVID 19 all comers

NCT04330638, 0 NCT04330638

tocilizumab vs. standard of care

COVID 19 all comers

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