ACTIV-1 abatacept, 2020 NCT04593940
abatacept vs. placebo
COVID-19 severe or critically
Fakharian, 2021 IRCT20151227025726N2
adalimumab vs. standard of care
COVID-19 severe or critically
Ana-COVID (Huet), 2020
anakinra vs. control
COVID-19 severe or critically
Kooistra, 2020
anakinra vs. standard of care
COVID-19 severe or critically
COV-BARRIER (critically ill), 2022 NCT04421027
baricitinib vs. placebo
COVID-19 severe or critically
Tziolos, 2021
baricitinib vs. standard of care
COVID-19 severe or critically
CAN-COVID, 2020 NCT04362813
canakinumab vs. placebo
COVID-19 severe or critically
ACTIV-1 cenicriviroc, 2020 NCT04593940
cenicriviroc vs. placebo
COVID-19 severe or critically
NCT04343989, 0 NCT04343989
clazakizumab vs. placebo
COVID-19 severe or critically
FORCE , 0 NCT04371367
complement inhibitors vs. standard of care
COVID-19 severe or critically
CORIMUNO19-ECU, 0 NCT04346797
eculizumab vs. standard of care
COVID-19 severe or critically
ACTIV-1 infliximab, 0 NCT04593940
infliximab vs. placebo
COVID-19 severe or critically
Kumar, 2021 CTRI/2020/05/024959
itolizumab vs. standard of care
COVID-19 severe or critically
V.Lomakin (CORONA), 2021 NCT04397562
Levilimab vs. placebo
COVID-19 severe or critically
RUXCOVID, 0 NCT04362137
ruxolitinib vs. placebo
COVID-19 severe or critically
DEVENT, 0 NCT04377620
ruxolitinib vs. placebo
COVID-19 severe or critically
Cao, 2020
ruxolitinib vs. vitamin C
COVID-19 severe or critically
sarilumab Sanofi phase 3 US, 0 NCT04315298
sarilumab vs. control
COVID-19 severe or critically
ARI-RAF (Della-Torre), 2020
sarilumab vs. control
COVID-19 severe or critically
sarilumab Sanofi phase 3 outside US, 0
sarilumab vs. placebo
COVID-19 severe or critically
REMAP-CAP sarilumab, 2021 NCT02735707
sarilumab vs. standard of care
COVID-19 severe or critically
CORIMUNO-VIRO, 0 NCT04341870
sarilumab azithromycin hydroxychloroquine vs. sarilumab
COVID-19 severe or critically
Lescure (Sarilumab 400mg), 2021 NCT04327388
sarilumab high dose (400mg) vs. placebo
COVID-19 severe or critically
Lescure (Sarilumab 200mg), 2021 NCT04327388
sarilumab low dose (200mg) vs. placebo
COVID-19 severe or critically
TACROVID, 2021 NCT04341038
tacrolimus vs. standard of care
COVID-19 severe or critically
Singh (TD-0903 10mg), 2021 NCT04402866
TD-0903 10mg vs. placebo
COVID-19 severe or critically
Singh (TD-0903 1mg), 2021 NCT04402866
TD-0903 1mg vs. placebo
COVID-19 severe or critically
Singh (TD-0903 3mg), 2021 NCT04402866
TD-0903 3mg vs. placebo
COVID-19 severe or critically
Amra, 2021 IRCT20170207032444N3
thalidomide vs. standard of care
COVID-19 severe or critically
Karakike (ESCAPE), 2021 NCT04339712
tocilizumab vs. anakinra
COVID-19 severe or critically
Klopfenstein, 2020
tocilizumab vs. control
COVID-19 severe or critically
Somers, 2020
tocilizumab vs. control
COVID-19 severe or critically
Mathilde, 2020
tocilizumab vs. control
COVID-19 severe or critically
Andrew, 2020
tocilizumab vs. control
COVID-19 severe or critically
Biran, 2020
tocilizumab vs. control
COVID-19 severe or critically
TOCI-RAF Study Group (Campochiaro), 2020
tocilizumab vs. control
COVID-19 severe or critically
Rashad, 2021 NCT04519385
tocilizumab vs. dexamethasone
COVID-19 severe or critically
CORON-ACT, 0 NCT04335071
tocilizumab vs. placebo
COVID-19 severe or critically
COVACTA (Rosas), 2020 NCT04320615
tocilizumab vs. placebo
COVID-19 severe or critically
NCT04377750 (HMO-0224-20), 0 NCT04377750
tocilizumab vs. placebo
COVID-19 severe or critically
Rosas (REMDACTA), 2021 NCT04409262
tocilizumab vs. placebo
COVID-19 severe or critically
Sarhan, 2022 NCT04779047
tocilizumab vs. remdesivir
COVID-19 severe or critically
Rojas-Marte, 2020
tocilizumab vs. standard of care
COVID-19 severe or critically
Karampitsakos, 2021
tocilizumab vs. standard of care
COVID-19 severe or critically
REMAP-CAP (tocilizumab), 2021 NCT02735707
tocilizumab vs. standard of care
COVID-19 severe or critically
CORIMUNO-TOCI-ICU (Group 2), 2020 NCT04331808
tocilizumab vs. standard of care
COVID-19 severe or critically
Pereira, 2020
tocilizumab vs. standard of care
COVID-19 severe or critically
Veiga, 2021 NCT04403685
tocilizumab vs. standard of care
COVID-19 severe or critically
CORIMUNO-TOCI-1 (Group 1), 2020 NCT04331808
tocilizumab vs. standard of care
COVID-19 severe or critically
Talaschian, 2021 IRCT20081027001411N4
tocilizumab vs. standard of care
COVID-19 severe or critically
ChiCTR2000030580, 0 ChiCTR2000030580
tocilizumab vs. standard of care
COVID-19 severe or critically
Hamed, 2021
tocilizumab vs. standard of care
COVID-19 severe or critically
Sarhan, 2022 NCT04779047
tocilizumab vs. tocilizumab
COVID-19 severe or critically
MARIPOSA, 2021 NCT04363736
tocilizumab vs. tocilizumab
COVID-19 severe or critically
Belhassen-Garc??a, 2021
tocilizumab vs. tocilizumab
COVID-19 severe or critically