metaOBS - - Real World Evidence KB

Treatment relative effect with 95% CI; and degree of certainty (adaptated from GRADE). method

Treament	Trials	Summary Endpoints death D28 deaths deaths (time to event analysis only) clinical improvement clinical improvement (14-day) clinical improvement (time to event analysis only) death or ventilation hospital discharge mechanical ventilation off oxygenation superinfection core analysis (OBS if no RCT) RCTs only all (RCT+OBS)
Treament	Trials	clinical deterioration	clinical improvement	deaths	viral clearance
high-dose IFN beta-1a	0	-	-	-	-