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molnupiravir in COVID 19 outpatients - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsFischer (all doses), 2021 0.22 [0.01; 6.60] MOVe-OUT, 2021 0.06 [0.00; 1.05] 0.10[0.01; 0.92]Fischer (all doses), 2021, MOVe-OUT, 202120%964lownot evaluable deathsdetailed resultsFischer (all doses), 2021 0.22 [0.01; 6.60] MOVe-OUT, 2021 0.06 [0.00; 1.05] 0.10[0.01; 0.92]Fischer (all doses), 2021, MOVe-OUT, 202120%964lownot evaluable hospitalization or deathdetailed resultsMOVe-OUT, 2021 0.48 [0.30; 0.78] 0.48[0.30; 0.78]MOVe-OUT, 202110%762NAnot evaluable hospitalizationdetailed resultsMOVe-OUT, 2021 0.49 [0.30; 0.79] 0.49[0.30; 0.79]MOVe-OUT, 202110%762NAnot evaluable viral clearance detailed resultsFischer (all doses), 2021 14.50 [1.70; 123.69] 14.50[1.70; 123.69]Fischer (all doses), 202110%171NAnot evaluable viral clearance by day 7detailed resultsFischer (all doses), 2021 14.50 [1.70; 123.69] 14.50[1.70; 123.69]Fischer (all doses), 202110%171NAnot evaluable AE leading to drug discontinuationdetailed resultsFischer (all doses), 2021 0.88 [0.08; 9.94] MOVe-OUT, 2021 0.49 [0.23; 1.05] 0.51[0.25; 1.07]Fischer (all doses), 2021, MOVe-OUT, 202120%1,613lownot evaluable serious adverse eventsdetailed resultsFischer (all doses), 2021 1.34 [0.14; 13.10] MOVe-OUT, 2021 0.70 [0.48; 1.03] 0.71[0.49; 1.04]Fischer (all doses), 2021, MOVe-OUT, 202120%1,613lownot evaluable adverse eventsdetailed resultsFischer (all doses), 2021 1.05 [0.54; 2.02] MOVe-OUT, 2021 0.89 [0.71; 1.11] 0.90[0.73; 1.12]Fischer (all doses), 2021, MOVe-OUT, 202120%1,613lownot evaluable0.020.01.0relative treatment effectwww.metaEvidence.org2025-03-09 16:02 +01:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 97 - treatments: 941 - roots T: 290

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