Study Exclusion reasons Remarks Reference(s)
BREATH-19 Study, 0 single-arm  
Gritti et al., 2020 single-arm inadequate or absent control group

Gritti et al. medRxiv 10.1101/2020.04.01.20048561

 
Huijie Bian, 2020 non randomized controlled trial not relevant study design study with major methological limitations precluding any conclusion

Huijie Bian medRxiv 10.1101/2020.03.21.20040691

 
Yin Wang et al., 2020 retrospective cohort (registry) not relevant study design

Yin Wang et al. medRxiv 10.1101/2020.03.06.20032342

 
Roschewski, 2020 observational study no control group

Roschewski M Sci Immunol 2020 Jun 5;5(48):eabd0110. 10.1126/sciimmunol.abd0110

 
Bargay-Lleonart, 2022 randomized controlled trial no clinically relevant endpoint The trial was terminated early due to the impossibility of recruitment due to the pandemic.

Bargay-Lleonart J J Clin Med 2022 May 27;11(11):3039. 10.3390/jcm11113039

 
Dai W, 2020 retrospective cohort other inadequate statistical analysis

Wei Dai, Jian Wu, Tianfu Li, Jiawei Shen, Rongrong Pang, Bangshun He, Tao Luo, Yanju Guo, Yang Yang, Jun Zhao, Mingchao Zhang, Na Li, Ying Han, Qiuyue Wu, Weiwei Li, Xinyi Xia BMC Cardiovascular Diabetology

 
Bernaola, 2020 retrospective cohort other

Nikolas Bernaola medrxiv;2020.07.17.20155960v1 10.1101/2020.07.17.20155960

 
Holt, 2020 retrospective cohort other no CI reported

Holt, Gregory E 10.21203/rs.3.rs-39875/v1

 
Klopfenstein, 2020 retrospective cohort other major flaws in the method

Klopfenstein T International Journal of Infectious Diseases 10.1016/j.ijid.2020.08.024

 
Cantini, 2020 non randomized controlled trial other same patients than in Cantini et al. (octobre publication)

Cantini F J Infect 2020 Aug;81(2):318-356. 10.1016/j.jinf.2020.04.017