Study | Exclusion reasons | Remarks | Reference(s) | ||
---|---|---|---|---|---|
HYDRA, 2020 | randomized controlled trial | Initially found in Axfors et al. meta-analysis results published by Hernadez et al | |||
CloroCOVID19, 2020 | randomized controlled trial | inadequate or absent control group | This paper reports partial results from an unplanned interim analysis.Efficacy and safety criteria do not appear to have ever been assessed on the same number of patients (denominators are different for almost every criterion and are less than the number of patients randomized). Compared to the registration record, the patient eligibility criteria were changed. |
Borba JAMA Netw Open 2020; 3:e208857 10.1001/jamanetworkopen.2020.8857 Mayla Borba for CloroCovid-19 Team medRxiv 2020.04.07.20056424 |
|
ChiCTR2000029975, 0 | single-arm | not relevant study design | |||
Duke university (Hydroxychloroquine), 2020 | randomized controlled trial | cancelled by investigator | |||
ChiCTR2000029826 (Cancelled by the investigator), 0 | randomized controlled trial | cancelled by investigator | |||
Thakar, 2021 | randomized controlled trial | no clinically relevant endpoint |
Thakar A Indian J Med Res 2021 Jan 21. 10.4103/ijmr.IJMR_3665_20 |
||
Barbosa, 2020 | retrospective cohort | other | the only document variable for this study is a copy of a submission to NEJM. It is impossible to verify the veracity of this document. The paper was submitted apr 4th and since this date ther is no publication in NEJM or in other media (included preprint server). | ||
Mallat, 2020 | retrospective cohort | other | inapropriate statistical analysis. Time to events analyszed with means without taken into account the censure due to death or lost to follow-up |
Jihad Mallat, Fadi Hamed, Maher Balkis, Mohamed A Mohamed, Mohamad Mooty, Asim Malik, Ahmad Nusair, Fernanda Bonilla medRxiv 2020.04.27.20082180 10.1101/2020.04.27.20082180 |
|
Mehra, 2020 | retrospective cohort | other | the paper was retracted by 3 authors on June 4, 2020 |
Mehra MR Lancet 2020 May 22;S0140-6736(20)31180-6. 10.1016/S0140-6736(20)31180-6 Mehra MR Lancet 2020 Jun 13;395(10240):1820. 10.1016/S0140-6736(20)31324-6 |