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meta|IO

Evidence base on efficacy and safety of
Immuno-Oncology drugs

Global living systematic review and meta-analysis of RCTs

Latest studies

BCTOP-T-A01 arm A/B, 2024

es-BC - Triple negatif (TNBC) - (neo)adjuvant (NA)

gemcitabine plus platin

NCI 10013, 2022

es-BC - TNBC - NA - all population

atezolizumab plus carboplatin plus paclitaxel

TBCRC, 2024

la/mBC - TNBC - L2 - all population

carboplatin

SHR1210-III-322, 2024

es-BC - Triple negatif (TNBC) - (neo)adjuvant (NA)

camrelizumab plus SOC

NSABP B-59/GBG 96-GeparDouze, 2018

mBC - Triple negative (TNBC) - (neo)adjuvant (NA)

carboplatin

KEYNOTE-119 PD-L1 positive (CPS = 1 or more), 2019

la/mBC - TNBC - L2 - PDL1 positive

pembrolizumab alone

KEYNOTE-119 (PD-L1 positive CPS = 10 or more), 2019

la/mBC - TNBC - L2 - PDL1 positive

pembrolizumab alone

IMpassion-132 (PD-L1 positive population), 2024

la/mBC - TNBC - L2 - PDL1 positive

carboplatin

A-Brave Stratum A, 2024

es-BC - Triple negatif (TNBC) - (neo)adjuvant (NA)

avelumab alone

NeoTrip Michel Angelo, 2022

es-BC - TNBC - NA - all population

atezolizumab plus carboplatin plus nab-paclitaxel

TORCHLIGHT PDL 1 positive population, 2024

la/mBC - TNBC - L1 - PDL1 positive

nab-paclitaxel plus toripalimab

FUTURE-SUPER_immunomodulatory subtype, 2024

mBC - Triple negative (TNBC) - 1st Line (L1)

camrelizumab alone

TORCHLIGHT, 2024

la/mBC - TNBC - L1 - all population

nab-paclitaxel plus toripalimab

Alice, 2022

la/mBC - TNBC - L2 - all population

atezolizumab based treatment

ICON, 2024

la/mBC - HR positive - L2 - all population

nivolumab plus ipilimumab

Saphir02 Breast-Immuno, 2021

mBC - HER 2 negative

durvalumab alone

Modul Cohort 4, 2023

metastatic/advanced - colorectal cancer (mCRC)

atezolizumab plus cometinib

CONTACT-03, 2023

metastatic/advanced RCC (mRCC) - 2nd line (L2)

atezolizumab plus cabozantinib

CheckMate 9DW, 2024

mHCC - 1st line (L1)

nivolumab plus ipilimumab plus SoC

CARES-310, 2023

mHCC - 1st line (L1)

VEGF(R) inhibitor

457
treatments 		  408
studies 		  1388
references
This project is supported by H2020 Qualitop, an EU-funded project, Hospices Civils de Lyon and CNRS UMR5558 LBBE.
     

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